Configuration of Cyclic Amines with Bode’s Acylation Reagents

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A bis(silylene)-stabilized diphosphorus compound and its reactivity as a monophosphorus anion switch reagent

In distinction to the well-established transition-metal-mediated activation of white phosphorus (P4), the metal-free direct functionalization of P4 has remained uncommon. The conversion of P4 right into a reactive zero-valent diphosphorus compound (P2) has confirmed difficult to hold out with out counting on steel reactivity.
Herein, we describe the facile degradation of P4 mediated by two divalent silicon atoms in a bis(silylene) scaffold, leading to a silylene-stabilized zero-valent P2 advanced.
The presence of two lone pairs of electrons on every P atom within the silylene-stabilized P2 advanced allows a wealthy reactivity in direction of small molecules; response of the P2 species with CO2, water or a borane results in the formation of P-C, P-H or P-B bonds, respectively. Notably, the P2 advanced additionally serves as a single phosphorus anion (P) switch reagent in direction of steel carbonyls and a chlorogermylene compound, resulting in the synthetically helpful phosphaketenide (PCO) ligand and a phosphinidene germylene advanced, respectively.

Bovine Serum Albumin ? Heat Shock, Reagent Grade, pH 7.0

7917-25 each
EUR 294

Bovine Serum Albumin ? Heat Shock, Reagent Grade, pH 7.0

7917-5 each
EUR 144

ExoQualiTM Overall Exosome Isolation Reagent (from serum)

CEIK-044L-30T 30 T Ask for price

ExoQualiTM Overall Exosome Isolation Reagent (from serum)

CEIK-044L-50T 50 T Ask for price

Albumin Depletion Reagent for Plasma and Serum (10 ml) NEW!

P5W13 10 rxn
EUR 99

OPEF01351-100G - Human Serum Albumin Antigen Reagent Grade

OPEF01351-100G 100g
EUR 1302

Bovine Serum Albumin Fatty Acid Protease Free Reagent Grade

GWB-DCC190 1 kg Ask for price

MinuteTM Albumin Depletion Reagent for Plasma and Serum (20 ml)

WA-013 each
EUR 135

Albumin Bovine (pH 7) fraction V Reagent Grade (Bovine Serum Albumin, BSA), 99%

65186 10 Gms
EUR 38.4
Description: Part B

MOUSE SERUM Serum Products

GWB-Q00006 100 ml Ask for price

EZ-DNA Reagents

BS8202 100preps
EUR 105.67

EZ-DNA Reagents

SK8201 100preps
EUR 112.2

Ecl Detection Reagents

RPN3004 EACH
EUR 552.9

Ecl Detection Reagents - EACH

RPN2105 EACH
EUR 815.4

Mouse Serum

abx098261-100L 100 L
EUR 155407.2

Mouse Serum

20-abx098261
  • Ask for price
  • Ask for price
  • 100 ml
  • 10 ml

Mouse Serum

abx098261-5L 5 L
EUR 10599.6

Mouse Serum

abx098262-1ml 1 ml
EUR 2064

Mouse serum

IHR-8141 10 ml
EUR 47.75

Mouse Serum

M2021-050 500ml
EUR 970

Mouse Serum

abx098261-1ml 1 ml Ask for price

Mouse Serum

abx098261-200l 200 µl Ask for price

MOUSE SERUM

MBS238224-100mL 100mL
EUR 845

MOUSE SERUM

MBS238224-5x100mL 5x100mL
EUR 3620

CryoProtX Mix Reagents 1.5 mL

M-MDSR-61 1.5 ml ml
EUR 37
Description: CryoProtX Mix Reagents 1.5 mL

Mouse Serum - 100ml

MO-340/100 100ml
EUR 183.32

Mouse Serum - 500ml

MO-340/500 500ml
EUR 733.32

MOUSE SERUM WITH 0.09% AZIDE Serum Products

GWB-Q00007 5 ml Ask for price

MOUSE SERUM WITH 0.09% AZIDE Serum Products

GWB-Q00008 10 ml Ask for price

MOUSE SERUM WITH 0.09% AZIDE Serum Products

GWB-Q00009 50 ml Ask for price

Serum, Mouse

MBS638822-100mL 100mL
EUR 815

Serum, Mouse

MBS638822-5x100mL 5x100mL
EUR 3435

Set of 10 Biolipidure Reagents

Biolipidure-set 10mLx10
EUR 1820.4
Description: Set of 10 Biolipidure Reagents, whose applications include Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

REAGENTS HIGH RANGE AMMONIA - PK25

HI73325 PK25
EUR 55.35

High Range Ammonia Reagents - EACH

HI9373301 EACH
EUR 130.95

Mouse Serum Proteins goat polyclonal antibody, Serum

AP31483SU-N 1 ml Ask for price

Mouse Serum Proteins rabbit polyclonal antibody, Serum

AP31472SU-N 1 ml Ask for price

CryoProtX Mix Eco Reagents 1.5 mL

M-MDSR-61-ECO 1.5 ml ml
EUR 37
Description: CryoProtX Mix Eco Reagents 1.5 mL

PeliKine tool set, additional reagents

M1980 1 unit
EUR 169.8

Mouse Serum - 100 ml

CAMOU-1B each
EUR 554.28

Alkphos Direct Labelling Reagents - EACH

RPN3680 EACH
EUR 915.3

Mouse Serum Amyloid P Component (SAP) Reference serum

SAP12-RS 100 ul
EUR 388.8

Mouse Serum - 10ml

MO-340/10 10ml
EUR 28.11

Mouse Serum - 20ml

MO-340/20 20ml
EUR 55

Mouse Serum - 50ml

MO-340/50 50ml
EUR 97.79

Mouse Serum pool

MBS571968-1mL 1mL
EUR 160

Mouse Serum pool

MBS571968-5x1mL 5x1mL
EUR 575

Normal Mouse Serum

88-NM35 50 ml
EUR 459
Description: Normal Mouse Serum

Normal Mouse Serum

88R-1002 5 ml
EUR 118
Description: Normal Mouse Serum which has been lipid extracted and dialyzed against 10 mM Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Normal Mouse Serum

BMS0070-10mL 10 mL
EUR 89
Description: High quality Normal mouse serum processed from non-immunized normal adult mouses is used as a blocking agent or as a negative control for immunoassays.

Normal Mouse Serum

BMS0070-10mL10 10 mL×10
EUR 529
Description: High quality Normal mouse serum processed from non-immunized normal adult mouses is used as a blocking agent or as a negative control for immunoassays.

Normal Mouse Serum

NMS 1 ml/vial
EUR 91

Normal Mouse Serum

BMS0070-each each Ask for price

Normal Mouse Serum

MBS686158-5mL 5mL
EUR 180

Normal Mouse Serum

MBS686158-5x5mL 5x5mL
EUR 655

Normal Mouse Serum

MBS686304-2mL 2mL
EUR 150

Normal Mouse Serum

MBS686304-5x2mL 5x2mL
EUR 535

Normal Mouse Serum

MBS837810-5mL 5mL
EUR 300

Normal Mouse Serum

MBS837810-5x5mL 5x5mL
EUR 1210

Normal Mouse Serum

MBS539323-50mL 50mL
EUR 710

Normal Mouse Serum

MBS539323-5x50mL 5x50mL
EUR 2975

Normal Mouse Serum

MBS9718943-10mL 10mL
EUR 135

Normal Mouse Serum

MBS9718943-10x10mL 10x10mL
EUR 395

Mouse Serum Albumin

30R-3304 10 mg
EUR 153
Description: Purified native Mouse Serum Albumin

Mouse Serum Albumin

CSB-NP000801m 10mg Ask for price

Mouse Serum albumin

MBS571996-10mg 10mg
EUR 395

Mouse Serum albumin

MBS571996-5x10mg 5x10mg
EUR 1625

Mouse Serum Albumin

MBS717450-100mg 100mg
EUR 635

Mouse Serum Albumin

MBS717450-10mg 10mg
EUR 180

Mouse Serum Albumin

MBS717450-1g 1g
EUR 2930

Mouse Serum Albumin

MBS717450-1mg 1mg
EUR 135

Mouse Serum Albumin

MBS717450-5x1g 5x1g
EUR 13130

Mouse Serum Albumin

MBS7615609-INQUIRE INQUIRE Ask for price

Free Chlorine Reagents 0-5mg/L - EACH

WAT1028 EACH
EUR 49.95

Serum, Mouse, Normal

MBS638791-2mL 2mL
EUR 340

Serum, Mouse, Normal

MBS638791-5mL 5mL
EUR 475

Serum, Mouse, Normal

MBS638791-5x5mL 5x5mL
EUR 1990

Serum, Mouse, Normal

MBS638800-05mL 0.5mL
EUR 465

Serum, Mouse, Normal

MBS638800-5x05mL 5x0.5mL
EUR 1950

Serum, Mouse, Normal

MBS638811-5mL 5mL
EUR 505

Utilizing the Competing Enantioselective Conversion Methodology to Assign the Absolute Configuration of Cyclic Amines with Bode’s Acylation Reagents

The competing enantioselective conversion (CEC) methodology is a fast and dependable means to find out absolute configuration. Beforehand, Bode’s chiral acylated hydroxamic acids had been used to find out the stereochemistry of main amines, in addition to cyclic and acyclic secondary amines. The enantioselective acylation has been evaluated for 4-, 5-, and six-membered cyclic secondary amines, together with medicinally related compounds.
The constraints of the strategy had been studied by way of computational evaluation and experimental outcomes. Piperidines with substituents on the 2-position didn’t behave nicely except the axial conformer was energetically accessible, which is per the transition state geometries proposed by Bode and Kozlowski.
Management experiments had been carried out to analyze the reason for degrading selectivity below the CEC response circumstances. The current examine expands the scope of the CEC methodology for secondary amines and offers a greater understanding of the response profile.

Synthesis of Alkyl Silanes through Response of Unactivated Alkyl Chlorides and Triflates with Silyl Lithium Reagents

The response of unactivated secondary and first alkyl chlorides in addition to main alkyl triflates with silyl lithium reagents to entry tetraorganosilanes is reported. These nucleophilic substitutions proceed within the absence of any transition steel catalyst below delicate circumstances in average to excellent yields. The silyl lithium reagents are readily generated from the corresponding commercially obtainable chlorosilanes. Enantioenriched secondary alkyl chlorides react with excessive stereospecificity below inversion of configuration.

Floor-enhanced Raman Scattering Detection of Nucleic Acids exhibiting Sterically Accessible Guanines utilizing Ruthenium-polypyridyl Reagents

Right here, we report the applying of surface-enhanced Raman scattering (SERS) spectroscopy as a speedy and sensible device for assessing the formation of coordinative adducts between nucleic acid guanines and ruthenium polypyridyl reagents. The know-how offers a sensible method for the wash-free and fast identification of nucleic acid buildings exhibiting sterically accessible guanines.
That is demonstrated for the detection of a quadruplex-forming sequence current within the promoter area of the c-myc oncogene, which reveals a non-paired, reactive guanine at a flanking place of the G-quartets.
A DFT Examine on Fe I/Fe II/Fe III Mechanism of the Cross-Coupling between Haloalkane and Aryl Grignard Reagent Catalyzed by Iron-SciOPP Complexes
To discover believable response pathways of the cross-coupling response between a haloalkane and an aryl steel reagent catalyzed by an iron-phosphine advanced, we look at the response of FeBrPh(SciOPP) <b>1</b> and bromocycloheptane using density purposeful concept (DFT) calculations.
Moreover the cross-coupling, we additionally examined the aggressive pathways of β-hydrogen elimination to provide the corresponding alkene byproduct. The DFT examine on the response pathways explains the cross-coupling selectivity over the elimination by way of Fe<sup>I</sup>/Fe<sup>II/</sup>Fe<sup>III</sup> mechanism which includes the era of alkyl radical intermediates and their propagation in a series response method.
The current examine offers perception into the detailed molecular mechanic of the cross-coupling response and revises the Fe<sup>II</sup>/Fe<sup>II</sup> mechanisms beforehand proposed by us and others

ExoQualiTM Overall Exosome Isolation Reagent (from serum)

CEIK-044L-30T 30 T Ask for price

ExoQualiTM Overall Exosome Isolation Reagent (from serum)

CEIK-044L-50T 50 T Ask for price

Albumin Depletion Reagent for Plasma and Serum (10 ml) NEW!

P5W13 10 rxn
EUR 99

OPEF01351-100G - Human Serum Albumin Antigen Reagent Grade

OPEF01351-100G 100g
EUR 1302

Bovine Serum Albumin Fatty Acid Protease Free Reagent Grade

GWB-DCC190 1 kg Ask for price

MinuteTM Albumin Depletion Reagent for Plasma and Serum (20 ml)

WA-013 each
EUR 135

Albumin Bovine (pH 7) fraction V Reagent Grade (Bovine Serum Albumin, BSA), 99%

65186 10 Gms
EUR 38.4
Description: Part B

MOUSE SERUM Serum Products

GWB-Q00006 100 ml Ask for price

EZ-DNA Reagents

BS8202 100preps
EUR 105.67

EZ-DNA Reagents

SK8201 100preps
EUR 112.2

Ecl Detection Reagents

RPN3004 EACH
EUR 552.9

Ecl Detection Reagents - EACH

RPN2105 EACH
EUR 815.4

Mouse Serum

abx098261-100L 100 L
EUR 155407.2

Mouse Serum

20-abx098261
  • Ask for price
  • Ask for price
  • 100 ml
  • 10 ml

Mouse Serum

abx098261-5L 5 L
EUR 10599.6

Mouse Serum

abx098262-1ml 1 ml
EUR 2064

Mouse serum

IHR-8141 10 ml
EUR 47.75

Mouse Serum

M2021-050 500ml
EUR 970

Mouse Serum

abx098261-1ml 1 ml Ask for price

Mouse Serum

abx098261-200l 200 µl Ask for price

MOUSE SERUM

MBS238224-100mL 100mL
EUR 845

MOUSE SERUM

MBS238224-5x100mL 5x100mL
EUR 3620

CryoProtX Mix Reagents 1.5 mL

M-MDSR-61 1.5 ml ml
EUR 37
Description: CryoProtX Mix Reagents 1.5 mL

Mouse Serum - 100ml

MO-340/100 100ml
EUR 183.32

Mouse Serum - 500ml

MO-340/500 500ml
EUR 733.32

MOUSE SERUM WITH 0.09% AZIDE Serum Products

GWB-Q00007 5 ml Ask for price

MOUSE SERUM WITH 0.09% AZIDE Serum Products

GWB-Q00008 10 ml Ask for price

MOUSE SERUM WITH 0.09% AZIDE Serum Products

GWB-Q00009 50 ml Ask for price

Serum, Mouse

MBS638822-100mL 100mL
EUR 815

Serum, Mouse

MBS638822-5x100mL 5x100mL
EUR 3435

Set of 10 Biolipidure Reagents

Biolipidure-set 10mLx10
EUR 1820.4
Description: Set of 10 Biolipidure Reagents, whose applications include Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

REAGENTS HIGH RANGE AMMONIA - PK25

HI73325 PK25
EUR 55.35

High Range Ammonia Reagents - EACH

HI9373301 EACH
EUR 130.95

Mouse Serum Proteins goat polyclonal antibody, Serum

AP31483SU-N 1 ml Ask for price

Mouse Serum Proteins rabbit polyclonal antibody, Serum

AP31472SU-N 1 ml Ask for price

CryoProtX Mix Eco Reagents 1.5 mL

M-MDSR-61-ECO 1.5 ml ml
EUR 37
Description: CryoProtX Mix Eco Reagents 1.5 mL

PeliKine tool set, additional reagents

M1980 1 unit
EUR 169.8

Mouse Serum - 100 ml

CAMOU-1B each
EUR 554.28

Alkphos Direct Labelling Reagents - EACH

RPN3680 EACH
EUR 915.3

Mouse Serum Amyloid P Component (SAP) Reference serum

SAP12-RS 100 ul
EUR 388.8

Mouse Serum - 10ml

MO-340/10 10ml
EUR 28.11

Mouse Serum - 20ml

MO-340/20 20ml
EUR 55

Mouse Serum - 50ml

MO-340/50 50ml
EUR 97.79

Mouse Serum pool

MBS571968-1mL 1mL
EUR 160

Mouse Serum pool

MBS571968-5x1mL 5x1mL
EUR 575

Normal Mouse Serum

88-NM35 50 ml
EUR 459
Description: Normal Mouse Serum

Normal Mouse Serum

88R-1002 5 ml
EUR 118
Description: Normal Mouse Serum which has been lipid extracted and dialyzed against 10 mM Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Normal Mouse Serum

BMS0070-10mL 10 mL
EUR 89
Description: High quality Normal mouse serum processed from non-immunized normal adult mouses is used as a blocking agent or as a negative control for immunoassays.

Normal Mouse Serum

BMS0070-10mL10 10 mL×10
EUR 529
Description: High quality Normal mouse serum processed from non-immunized normal adult mouses is used as a blocking agent or as a negative control for immunoassays.

Normal Mouse Serum

NMS 1 ml/vial
EUR 91

Normal Mouse Serum

BMS0070-each each Ask for price

Normal Mouse Serum

MBS686158-5mL 5mL
EUR 180

Normal Mouse Serum

MBS686158-5x5mL 5x5mL
EUR 655

Normal Mouse Serum

MBS686304-2mL 2mL
EUR 150

Normal Mouse Serum

MBS686304-5x2mL 5x2mL
EUR 535

Normal Mouse Serum

MBS837810-5mL 5mL
EUR 300

Normal Mouse Serum

MBS837810-5x5mL 5x5mL
EUR 1210

Normal Mouse Serum

MBS539323-50mL 50mL
EUR 710

Normal Mouse Serum

MBS539323-5x50mL 5x50mL
EUR 2975

Normal Mouse Serum

MBS9718943-10mL 10mL
EUR 135

Normal Mouse Serum

MBS9718943-10x10mL 10x10mL
EUR 395

Mouse Serum Albumin

30R-3304 10 mg
EUR 153
Description: Purified native Mouse Serum Albumin

Mouse Serum Albumin

CSB-NP000801m 10mg Ask for price

Mouse Serum albumin

MBS571996-10mg 10mg
EUR 395

Mouse Serum albumin

MBS571996-5x10mg 5x10mg
EUR 1625

Mouse Serum Albumin

MBS717450-100mg 100mg
EUR 635

Mouse Serum Albumin

MBS717450-10mg 10mg
EUR 180

Mouse Serum Albumin

MBS717450-1g 1g
EUR 2930

Mouse Serum Albumin

MBS717450-1mg 1mg
EUR 135

Mouse Serum Albumin

MBS717450-5x1g 5x1g
EUR 13130

Mouse Serum Albumin

MBS7615609-INQUIRE INQUIRE Ask for price

Free Chlorine Reagents 0-5mg/L - EACH

WAT1028 EACH
EUR 49.95

Serum, Mouse, Normal

MBS638791-2mL 2mL
EUR 340

Serum, Mouse, Normal

MBS638791-5mL 5mL
EUR 475

Serum, Mouse, Normal

MBS638791-5x5mL 5x5mL
EUR 1990

Serum, Mouse, Normal

MBS638800-05mL 0.5mL
EUR 465

Serum, Mouse, Normal

MBS638800-5x05mL 5x0.5mL
EUR 1950

Serum, Mouse, Normal

MBS638811-5mL 5mL
EUR 505

Serum, Mouse, Normal

MBS638811-5x5mL 5x5mL
EUR 2125

Haptoglobin, Mouse Serum

MBS173102-01mg 0.1mg
EUR 865

Haptoglobin, Mouse Serum

MBS173102-1mg 1mg
EUR 2650

Haptoglobin, Mouse Serum

MBS173102-5x1mg 5x1mg
EUR 11715

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